Matchmaking Neuroscience meets Bioinformatics

4 Sept – 18 Oct 2023 | Wroclaw, Poland

Ebru Ercan-Herbst

Research Group Leader

BioMed X Institute

Heidelberg, Germany

4 profile visits

iPSC-based in vitro disease modeling. White matter deficits in schizophrenia. nucRNA-seq from post-mortem human brain.

About me

My research primarily focuses on investigating neuron-oligodendrocyte interactions and identifying the molecular mechanisms underlying myelination deficits. During my postdoctoral studies at Harvard Medical School, my work centered around autism spectrum disorders, where I discovered a neuronal factor that hinders oligodendrocyte development, leading to deficits in myelination. Over the past four years, I have been leading a team of scientists at the BioMed X Institute in Heidelberg. My research revolves around exploring early intervention strategies for schizophrenia, with a specific emphasis on the hypomyelination pathology. In pursuit of these goals, my team develops physiologically-relevant in vivo and in vitro platforms. We also employ transcriptomics analysis on post-mortem brain samples to identify potential factors contributing to hypomyelination pathology of schizophrenia.

My organisation

BioMed X Institute

Social media

Skills

  • iPSC
  • Biochemistry
  • nucRNA-seq
  • cell biology
  • 3D-cultures
  • Disease modeling
  • neuroscience

Interests

  • schizophrenia
  • myelination
  • white matter
  • iPSC models
  • oligodendrocyte-neuron interaction
  • Disease modeling
  • 3D-cultures
  • organoids
  • Data Analysis
  • neuroscience

Additional questions

Organization types

Company

Activities

BioinformaticsNeuroscience

Country

Germany

Participant's current Engagement in EU projects

Project idea under development