Andrei Cismaru

Hi, I’m Andrei Cismaru, a medical oncologist and postdoctoral researcher in the Genomics department of the Institute of Biomedical Research—MEDFUTURE, the University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca.

I’m passionate about cancerogenesis, tumor growth, progression, and metastasis, as well as resistance to anticancer therapy. My current work is focused on developing strategies to overcome anticancer therapy resistance through novel drug discovery as well as means to enhance the immune response against cancer cells through various experimental models. Another focus of my work is on strategies to enhance the outcomes of hematopoietic stem cell transplantation

I carry out the clinical integration of essential omics data (proteomics, transcriptomics, metabolomics) in multiple research projects. This work enables me to obtain new perspectives on the molecular signature that characterizes different pathologies. I use omics data such as the mutational status of genes, microRNA, mRNA, protein expression, DNA methylation to study the complex interactions between multiple genetic and environmental factors that occur during the pathogenesis of diseases such as cancer. Obtaining specific molecular signatures enables further subtyping which lets me guide personalized treatments and provide a clear understanding of disease prognosis and progression.

Furthermore, as prevention is always better than treatment, I’m dedicated to developing and implementing CANCER SCREENING tools, directly contributing to improved patient outcomes, but also maximizing the return of investment in healthcare and perpetuating the cycle of innovation.

I am committed to encouraging collaboration and interdisciplinary partnerships between basic scientists, clinicians, and even industry partners to incorporate diverse perspectives and expertise to address complex healthcare issues effectively. I want to prioritize funding, infrastructure, and expertize towards projects with the greatest potential to directly impact patient care.