MEIHONG XU

Assoc Prof. at the School of Public Health, Peking University. My research focuses on the role of food-derived bioactive substances (e.g., bioactive peptides, nucleotides, beta-glucans) in anti-aging and healthy aging, with a particular emphasis on nutritional interventions for age-related degenerative diseases.

Key Research Contributions

1. Anti-Aging Mechanisms of Bioactive Peptides

   • Led a study using intestinal organoid chips to demonstrate that ginseng oligopeptides inhibit excessive cell proliferation, enhance antioxidant capacity (e.g., reducing HO₂ levels), and promote mucus secretion in aged gut models, offering new insights for maintaining intestinal health in老龄化 populations .

   • Investigated the effects of peptide-based interventions (e.g., collagen-derived peptides) on mitigating sarcopenia and neuroinflammation in animal models of Alzheimer’s and Parkinson’s diseases .

2. Nucleotides and Healthy Aging

   • Co-led the first-in-China human trial on nucleotide supplementation, showing significant telomere shortening、immune rejuvenation, and prevention of muscle atrophy in middle-aged and elderly participants .

   • Authored authoritative texts like Nucleotide Nutrition and Geriatric Nutrition, shaping academic frameworks for nucleotide research and application .

3. Nutritional Assessment Innovations

   • Developed the photo-assisted dietary intake (PAD) method, validated in both college students and elderly individuals, to improve dietary assessment accuracy in diverse populations, particularly in complex Chinese culinary settings